“Prevalence of BK Virus in Post-Renal Transplant Patients: Insights from a Single-Center Study”

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Case Report | Volume 16 Issue 1 (Jan-Dec, 2023) | Pages 1 - 4

“Prevalence of BK Virus in Post-Renal Transplant Patients: Insights from a Single-Center Study”

Syed Munib

Jehanzeb

Muhammad Shaid

Syed Arif

⁴

Fazal Wahab

Zafar Ahmed Khan

⁵

Associate Professor, Institute of Kidney Diseases Hayatabad Medical complex , Peshawar, Pakistan

Consultant ,Institute of Kidney Diseases Hayatabad Medical complex , Peshawar, Pakistan

DHQ Hospital Batkala, Pakistan

⁴

Consultant, Mian Gul Abdul haq jehanzeb Kidney Hospital, Swat, Pakistan

⁵

Assistant Professor Urology, MMC Hospital, Mardan, Pakistan

Under a Creative Commons license

Open Access

Received

Jan. 10, 2023

Revised

March 15, 2023

Accepted

Aug. 20, 2023

Published

Nov. 30, 2023

Abstract

Background: To retrospectively analyze post renal transplant patients to determine the frequency of BK-Virus infection, treatment and complication at Institute of Kidney Diseases Hayatabad, Peshawar. Methodology: This was a cross sectional (retrospective) study from January 2008 to January 2021 conducted at Institute of Kidney Diseases, Peshawar, Pakistan. Clinical Records and laboratory data were collected. BK viral load was obtained by quantitative DNA-polymerase chain reaction (PCR) testing of blood. Results: Total of 263 patients were assessed. Out of 263, 246 (93.54%) were males and 17 (6.46%) were females with mean age 32.06 ± 5.49. All patients underwent live related transplant. BK-Virus plasma PCR was positive in 15 (5.70%) in post renal transplant patients after 6 months. Conclusion: The BK-Virus infection is very common in post renal transplant patients who have received induction therapy and on intense immunosuppression. Effective Treatment is by reducing the immunosuppressive drugs to minimal level.

Keywords

BK-Virus

Kidney Transplantation.