Probiotics have been extensively studied in recent times for their health-promoting effects. Probiotics are usually used in the form of foods or food supplements. Probiotic bacteria seem to affect both oral health and immune responses. Probiotics provide an effective alternative way to combat periodontal diseases. In recent times there has been an increase in the incidence of antibiotic resistance, and usage of probiotics could be a promising field of research in the treatment of periodontitis.